Margaret Marie Isaacson, 76, of Lexington, MO passed away Sunday, September 19, 2010 in Odessa. Margaret Isaacson was born November 10, 1933 in Lexington, the daughter of Ralph Henry and Mary Marie Catherine Harrison Hoeppner. She was the owner and operator of Isaacson Boarding Home on South 13 Highway for 17 years. Margaret married Jesse Epperly, then Don Saddoris, and July 9, 1973 she married Donald �Ike� Isaacson. She is survived by her husband, Ike Isaacson, two children: Jimmie Epperly of Lexington and Donna Helms, Urich, MO. Four grandchildren, Kandi, Jesse, Jeff, and Davin. Four great-grandchildren: Jessica, Ronnie, Hayley and Nathan. One brother, Leroy, and wife, Sandi, Blue Springs, MO. Two sisters: Judy Shelby and husband, Jim, Lexington and Linda Julien and husband, Rick, Richmond. Preceding her in death were her husbands, Jesse Epperly and Don Saddoris, her parents, and four brothers, Ralph L. Hoeppner, John A. Hoeppner, Benjamin H. Hoeppner, and Crawford Hoeppner. Services will be 11:00 a.m., Wednesday, September 22, 2010 at the Walker-Nadler-Fuller Funeral Home, Lexington. Burial in Lexington Memory Gardens. Visitation from 6 to 8 p.m. Tuesday, September 21 at the funeral home. Memorials may be made to the Warrensburg Veterans Administration Volunteers. Arrangements by: Walker-Nadler-Fuller Funeral Home, 1720 South Street, Lexington, MO 64067 (660)259-2245